TY - JOUR T1 - Does diet quality matter? A secondary analysis of a randomized clinical trial. AU - Kahleova,Hana, AU - Brennan,Haley, AU - Znayenko-Miller,Tatiana, AU - Holubkov,Richard, AU - Barnard,Neal D, Y1 - 2023/11/28/ PY - 2023/9/7/received PY - 2023/11/9/accepted PY - 2023/10/31/revised PY - 2024/3/13/medline PY - 2023/11/28/pubmed PY - 2023/11/27/entrez SP - 270 EP - 273 JF - European journal of clinical nutrition JO - Eur J Clin Nutr VL - 78 IS - 3 N2 - This secondary analysis assessed the association of a plant-based index (PDI), healthful (hPDI), and unhealthful (uPDI), with weight loss in overweight adults. Participants (n = 244) were randomly assigned to a vegan (n = 122) or control group (n = 122) for 16 weeks. Three-day dietary records were analyzed and PDI indices were calculated. A repeated measure ANOVA was used for statistical analysis. All three scores increased in the vegan group; the effect sizes were: PDI +10.6 (95% CI +8.6 to +12.6; p < 0.001); hPDI +10.9 (95% CI +8.4 to +13.4; p < 0.001); and uPDI +5.4 (95% CI +3.4 to +7.4; p < 0.001). The change in all three scores significantly correlated with change in body weight: PDI (r = -0.40; p < 0.001); hPDI (r = -0.37; p < 0.001); and uPDI (r = -0.21; p = 0.002). These findings suggest that minimizing the consumption of animal products and oil may be an effective weight loss strategy in overweight adults. ClinicalTrials.gov number, NCT02939638. SN - 1476-5640 UR - https://www.unboundmedicine.com/medline/citation/38012413/full_citation DB - PRIME DP - Unbound Medicine ER -