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Physical activity and risk of severe gastrointestinal hemorrhage in older persons.
JAMA 1994 Aug 24-31; 272(8):595-9JAMA

Abstract

OBJECTIVE

To assess whether regular physical activity is associated with a decreased risk of severe gastrointestinal hemorrhage (GIH) in older persons.

DESIGN

Cohort study with 3 years of follow-up.

SETTING

Three communities of the Established Populations for Epidemiologic Studies of the Elderly.

PARTICIPANTS

A total of 8205 persons aged 68 years or older, yielding 22,277 person-years of follow-up.

MEASUREMENTS

The occurrence of severe GIH was defined as either a hospital discharge diagnosis of gastrointestinal bleeding associated with blood transfusion or death during the hospital stay or a nonhospital death with mention of GIH on the death certificate. Physical activity was measured by self-reported frequency of walking, gardening, or doing vigorous physical activity. Those participants doing the activity three times per week or more were compared with the remaining participants. Adjusted relative risks (RRs) of GIH were controlled for age, gender, body mass index, blood pressure, chronic conditions, number of hospital admissions in the past year, and number and types of drugs taken.

RESULTS

Severe GIH occurred in 241 participants (rate, 10.8 per 1000 person-years). After adjusting for potential confounding variables, the RRs and 95% confidence intervals (CIs) for severe GIH associated with walking, gardening, and vigorous physical activity were 0.6 (0.4 to 0.8), 0.8 (0.5 to 1.1), and 0.7 (0.4 to 1.2), respectively. The RR associated with a summary variable for the three activities was 0.7 (95% CI, 0.5 to 0.9). These results were consistent after stratifying on health status and disability or by excluding those who were not mobile, ie, not able to walk half a mile or climb a flight of stairs.

CONCLUSIONS

Regular physical activity is associated with a decreased risk for severe GIH in older persons.

Authors+Show Affiliations

Department of Gerontology, Catholic University, Rome, Italy.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

8057514

Citation

Pahor, M, et al. "Physical Activity and Risk of Severe Gastrointestinal Hemorrhage in Older Persons." JAMA, vol. 272, no. 8, 1994, pp. 595-9.
Pahor M, Guralnik JM, Salive ME, et al. Physical activity and risk of severe gastrointestinal hemorrhage in older persons. JAMA. 1994;272(8):595-9.
Pahor, M., Guralnik, J. M., Salive, M. E., Chrischilles, E. A., Brown, S. L., & Wallace, R. B. (1994). Physical activity and risk of severe gastrointestinal hemorrhage in older persons. JAMA, 272(8), pp. 595-9.
Pahor M, et al. Physical Activity and Risk of Severe Gastrointestinal Hemorrhage in Older Persons. JAMA. 1994;272(8):595-9. PubMed PMID: 8057514.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Physical activity and risk of severe gastrointestinal hemorrhage in older persons. AU - Pahor,M, AU - Guralnik,J M, AU - Salive,M E, AU - Chrischilles,E A, AU - Brown,S L, AU - Wallace,R B, PY - 1994/8/24/pubmed PY - 1994/8/24/medline PY - 1994/8/24/entrez SP - 595 EP - 9 JF - JAMA JO - JAMA VL - 272 IS - 8 N2 - OBJECTIVE: To assess whether regular physical activity is associated with a decreased risk of severe gastrointestinal hemorrhage (GIH) in older persons. DESIGN: Cohort study with 3 years of follow-up. SETTING: Three communities of the Established Populations for Epidemiologic Studies of the Elderly. PARTICIPANTS: A total of 8205 persons aged 68 years or older, yielding 22,277 person-years of follow-up. MEASUREMENTS: The occurrence of severe GIH was defined as either a hospital discharge diagnosis of gastrointestinal bleeding associated with blood transfusion or death during the hospital stay or a nonhospital death with mention of GIH on the death certificate. Physical activity was measured by self-reported frequency of walking, gardening, or doing vigorous physical activity. Those participants doing the activity three times per week or more were compared with the remaining participants. Adjusted relative risks (RRs) of GIH were controlled for age, gender, body mass index, blood pressure, chronic conditions, number of hospital admissions in the past year, and number and types of drugs taken. RESULTS: Severe GIH occurred in 241 participants (rate, 10.8 per 1000 person-years). After adjusting for potential confounding variables, the RRs and 95% confidence intervals (CIs) for severe GIH associated with walking, gardening, and vigorous physical activity were 0.6 (0.4 to 0.8), 0.8 (0.5 to 1.1), and 0.7 (0.4 to 1.2), respectively. The RR associated with a summary variable for the three activities was 0.7 (95% CI, 0.5 to 0.9). These results were consistent after stratifying on health status and disability or by excluding those who were not mobile, ie, not able to walk half a mile or climb a flight of stairs. CONCLUSIONS: Regular physical activity is associated with a decreased risk for severe GIH in older persons. SN - 0098-7484 UR - https://www.unboundmedicine.com/medline/citation/8057514/full_citation L2 - https://jamanetwork.com/journals/jama/fullarticle/vol/272/pg/595 DB - PRIME DP - Unbound Medicine ER -