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Disaccharide digestion and maldigestion.
Scand J Gastroenterol Suppl 1996; 216:111-21SJ

Abstract

All food carbohydrates are hydrolysed to monosaccharides before transport across the microvillus membrane. The digestion of disaccharides and some oligosaccharides is undertaken by a number of small intestinal brush border enzymes: sucrase-isomaltase, lactase phlorizinhydrolase, maltase-glycoamylase and trehalase. The distribution of the enzymes in the small intestine has been investigated. Different disaccharide maldigestion syndromes have been described. Lactase deficiency in adults is a condition found in the majority of inhabitants of the world. However, the prevalence varies widely between different populations. Sucrase-isomaltase deficiency is a very rare congenital condition except in Greenland. Trehalose maldigestion is likewise rare outside Greenland. Different hypotheses regarding the molecular background of the maldigestion syndromes are discussed.

Authors+Show Affiliations

Dept. of Medical Gastroenterology F, Gentofte University Hospital, Copenhagen, Denmark.No affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

8726284

Citation

Gudmand-Høyer, E, and H Skovbjerg. "Disaccharide Digestion and Maldigestion." Scandinavian Journal of Gastroenterology. Supplement, vol. 216, 1996, pp. 111-21.
Gudmand-Høyer E, Skovbjerg H. Disaccharide digestion and maldigestion. Scand J Gastroenterol Suppl. 1996;216:111-21.
Gudmand-Høyer, E., & Skovbjerg, H. (1996). Disaccharide digestion and maldigestion. Scandinavian Journal of Gastroenterology. Supplement, 216, pp. 111-21.
Gudmand-Høyer E, Skovbjerg H. Disaccharide Digestion and Maldigestion. Scand J Gastroenterol Suppl. 1996;216:111-21. PubMed PMID: 8726284.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Disaccharide digestion and maldigestion. AU - Gudmand-Høyer,E, AU - Skovbjerg,H, PY - 1996/1/1/pubmed PY - 1996/1/1/medline PY - 1996/1/1/entrez SP - 111 EP - 21 JF - Scandinavian journal of gastroenterology. Supplement JO - Scand. J. Gastroenterol. Suppl. VL - 216 N2 - All food carbohydrates are hydrolysed to monosaccharides before transport across the microvillus membrane. The digestion of disaccharides and some oligosaccharides is undertaken by a number of small intestinal brush border enzymes: sucrase-isomaltase, lactase phlorizinhydrolase, maltase-glycoamylase and trehalase. The distribution of the enzymes in the small intestine has been investigated. Different disaccharide maldigestion syndromes have been described. Lactase deficiency in adults is a condition found in the majority of inhabitants of the world. However, the prevalence varies widely between different populations. Sucrase-isomaltase deficiency is a very rare congenital condition except in Greenland. Trehalose maldigestion is likewise rare outside Greenland. Different hypotheses regarding the molecular background of the maldigestion syndromes are discussed. SN - 0085-5928 UR - https://www.unboundmedicine.com/medline/citation/8726284/full_citation L2 - https://medlineplus.gov/carbohydratemetabolismdisorders.html DB - PRIME DP - Unbound Medicine ER -