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Effectiveness of influenza vaccine in reducing hospital admissions in people with diabetes.

Abstract

The effectiveness of influenza vaccination in reducing hospitalization of people with diabetes for influenza, pneumonia, or diabetic events during influenza epidemics was assessed in a case control study in Leicestershire, England. Cases were 80 patients on the Leicestershire Diabetes Register who were admitted and discharged from hospital with International Classification of Disease codes for pneumonia, bronchitis, influenza, diabetic ketoacidosis, coma and diabetes, without mention of complications, during the influenza epidemics of 1989-90 and 1993. One hundred and sixty-controls, who were not admitted to hospital during this period, were randomly selected from the Register. Immunization against influenza was assessed in 37 cases and 77 controls for whom consent was obtained to access their clinical notes and for whom notes were available. Significant association was detected between reduction in hospitalization and influenza vaccination during the period immediately preceding an epidemic. Multiple logistic regression analysis estimated that influenza vaccination reduced hospital admissions by 79% (95% CI 19-95%) during the two epidemics, after adjustment for potential confounders.

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  • PMC Free Full Text
  • Authors

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    Source

    Epidemiology and infection 119:3 1997 Dec pg 335-41

    MeSH

    Adolescent
    Adult
    Aged
    Aged, 80 and over
    Case-Control Studies
    Diabetes Complications
    Disease Outbreaks
    England
    Female
    Hospitalization
    Humans
    Influenza Vaccines
    Influenza, Human
    Logistic Models
    Male
    Middle Aged
    Registries

    Pub Type(s)

    Comparative Study
    Journal Article
    Research Support, Non-U.S. Gov't

    Language

    eng

    PubMed ID

    9440437

    Citation

    TY - JOUR T1 - Effectiveness of influenza vaccine in reducing hospital admissions in people with diabetes. AU - Colquhoun,A J, AU - Nicholson,K G, AU - Botha,J L, AU - Raymond,N T, PY - 1998/1/24/pubmed PY - 1998/1/24/medline PY - 1998/1/24/entrez SP - 335 EP - 41 JF - Epidemiology and infection JO - Epidemiol. Infect. VL - 119 IS - 3 N2 - The effectiveness of influenza vaccination in reducing hospitalization of people with diabetes for influenza, pneumonia, or diabetic events during influenza epidemics was assessed in a case control study in Leicestershire, England. Cases were 80 patients on the Leicestershire Diabetes Register who were admitted and discharged from hospital with International Classification of Disease codes for pneumonia, bronchitis, influenza, diabetic ketoacidosis, coma and diabetes, without mention of complications, during the influenza epidemics of 1989-90 and 1993. One hundred and sixty-controls, who were not admitted to hospital during this period, were randomly selected from the Register. Immunization against influenza was assessed in 37 cases and 77 controls for whom consent was obtained to access their clinical notes and for whom notes were available. Significant association was detected between reduction in hospitalization and influenza vaccination during the period immediately preceding an epidemic. Multiple logistic regression analysis estimated that influenza vaccination reduced hospital admissions by 79% (95% CI 19-95%) during the two epidemics, after adjustment for potential confounders. SN - 0950-2688 UR - https://www.unboundmedicine.com/medline/citation/9440437/full_citation L2 - http://www.ncbi.nlm.nih.gov/pmc/articles/pmid/9440437/ ER -