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Pharmacological nutrition after burn injury.

Abstract

Burn patients develop pathophysiological alterations, which include extensive nitrogen loss, malnutrition, markedly increased metabolic rate and immunologic deficiency. This predisposes burn patients to frequent infections, poor wound healing, increased length of hospitalization and increased mortality. The nutritional support requires high protein and high energy diets preferably administered enterally soon after injury. The effects of increased dietary components such as glutamine, arginine and (n-3) fatty acids and related compounds have been evaluated in burn victims. These components, when supplied in quantities two to seven times of those in normal diets of healthy persons, appear to have beneficial pharmacological effects on the pathophysiological alterations associated with burns. However, the efficacy of immune-enhancing diets remains to be convincingly shown.

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  • Publisher Full Text
  • Authors+Show Affiliations

    ,

    Centro de Química de Proteínas, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, 14049-900, S.P., Brazil.

    Source

    The Journal of nutrition 128:5 1998 May pg 797-803

    MeSH

    Arginine
    Burns
    Energy Intake
    Enteral Nutrition
    Fatty Acids, Omega-3
    Glutamine
    Humans

    Pub Type(s)

    Journal Article
    Research Support, Non-U.S. Gov't
    Review

    Language

    eng

    PubMed ID

    9566984

    Citation

    De-Souza, D A., and L J. Greene. "Pharmacological Nutrition After Burn Injury." The Journal of Nutrition, vol. 128, no. 5, 1998, pp. 797-803.
    De-Souza DA, Greene LJ. Pharmacological nutrition after burn injury. J Nutr. 1998;128(5):797-803.
    De-Souza, D. A., & Greene, L. J. (1998). Pharmacological nutrition after burn injury. The Journal of Nutrition, 128(5), pp. 797-803.
    De-Souza DA, Greene LJ. Pharmacological Nutrition After Burn Injury. J Nutr. 1998;128(5):797-803. PubMed PMID: 9566984.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Pharmacological nutrition after burn injury. AU - De-Souza,D A, AU - Greene,L J, PY - 1998/6/13/pubmed PY - 1998/6/13/medline PY - 1998/6/13/entrez SP - 797 EP - 803 JF - The Journal of nutrition JO - J. Nutr. VL - 128 IS - 5 N2 - Burn patients develop pathophysiological alterations, which include extensive nitrogen loss, malnutrition, markedly increased metabolic rate and immunologic deficiency. This predisposes burn patients to frequent infections, poor wound healing, increased length of hospitalization and increased mortality. The nutritional support requires high protein and high energy diets preferably administered enterally soon after injury. The effects of increased dietary components such as glutamine, arginine and (n-3) fatty acids and related compounds have been evaluated in burn victims. These components, when supplied in quantities two to seven times of those in normal diets of healthy persons, appear to have beneficial pharmacological effects on the pathophysiological alterations associated with burns. However, the efficacy of immune-enhancing diets remains to be convincingly shown. SN - 0022-3166 UR - https://www.unboundmedicine.com/medline/citation/9566984/full_citation L2 - https://academic.oup.com/jn/article-lookup/doi/10.1093/jn/128.5.797 DB - PRIME DP - Unbound Medicine ER -