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Sunlight exposure and risk of lens opacities in a population-based study: the Salisbury Eye Evaluation project.

Abstract

CONTEXT

Exposure to UV-B radiation in sunlight has been shown to increase the risk of cataract formation in high-risk occupational groups, but risk to the population has not been quantified.

OBJECTIVES

To determine the ocular exposure to UV-B radiation in sunlight for a population of older persons and to determine the association between UV-B and lens opacities.

DESIGN

The Salisbury Eye Evaluation project, a population-based cohort of older adults.

SETTING

Salisbury, Md.

PARTICIPANTS

A total of 2520 community-dwelling 65-year-old to 84-year-old adults in Salisbury, Md, from 1993 to 1995, of whom 26.4% were African Americans.

MAIN OUTCOME MEASURE

Association of photographically documented cortical opacity 3/16 or greater in at least 1 eye with ocular UV-B exposure, reported in Maryland sun-years of exposure.

RESULTS

The odds of cortical opacity increased with increasing ocular exposure to UV-B (odds ratio [OR], 1.10; 95% confidence interval [CI], 1.02-1.20). The relationship was similar for women (OR, 1.14; 95% CI, 1.00-1.30) and for African Americans (OR, 1.18; 95% CI, 1.04-1.33). Analyses of the ocular dose by each age group after the age of 30 years showed no vulnerable age group, suggesting damage is based on cumulative exposure.

CONCLUSIONS

Although this population of older Americans has relatively low ocular exposure to UV-B in sunlight, there is still an association between ocular exposure and increasing odds of cortical opacity. Our study found an association among African Americans, which, to our knowledge, has not been reported previously. All sex and racial groups would benefit from simple methods to avoid ocular sun exposure.

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  • Authors+Show Affiliations

    ,

    Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD 21287, USA. swest@dcpom.med.jhu.edu

    , , , , ,

    Source

    JAMA 280:8 1998 Aug 26 pg 714-8

    MeSH

    Aged
    Aged, 80 and over
    Cataract
    Female
    Humans
    Male
    Models, Theoretical
    Risk
    Sunlight
    Ultraviolet Rays

    Pub Type(s)

    Journal Article
    Research Support, Non-U.S. Gov't
    Research Support, U.S. Gov't, P.H.S.

    Language

    eng

    PubMed ID

    9728643

    Citation

    West, S K., et al. "Sunlight Exposure and Risk of Lens Opacities in a Population-based Study: the Salisbury Eye Evaluation Project." JAMA, vol. 280, no. 8, 1998, pp. 714-8.
    West SK, Duncan DD, Muñoz B, et al. Sunlight exposure and risk of lens opacities in a population-based study: the Salisbury Eye Evaluation project. JAMA. 1998;280(8):714-8.
    West, S. K., Duncan, D. D., Muñoz, B., Rubin, G. S., Fried, L. P., Bandeen-Roche, K., & Schein, O. D. (1998). Sunlight exposure and risk of lens opacities in a population-based study: the Salisbury Eye Evaluation project. JAMA, 280(8), pp. 714-8.
    West SK, et al. Sunlight Exposure and Risk of Lens Opacities in a Population-based Study: the Salisbury Eye Evaluation Project. JAMA. 1998 Aug 26;280(8):714-8. PubMed PMID: 9728643.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Sunlight exposure and risk of lens opacities in a population-based study: the Salisbury Eye Evaluation project. AU - West,S K, AU - Duncan,D D, AU - Muñoz,B, AU - Rubin,G S, AU - Fried,L P, AU - Bandeen-Roche,K, AU - Schein,O D, PY - 1998/9/5/pubmed PY - 2001/8/14/medline PY - 1998/9/5/entrez SP - 714 EP - 8 JF - JAMA JO - JAMA VL - 280 IS - 8 N2 - CONTEXT: Exposure to UV-B radiation in sunlight has been shown to increase the risk of cataract formation in high-risk occupational groups, but risk to the population has not been quantified. OBJECTIVES: To determine the ocular exposure to UV-B radiation in sunlight for a population of older persons and to determine the association between UV-B and lens opacities. DESIGN: The Salisbury Eye Evaluation project, a population-based cohort of older adults. SETTING: Salisbury, Md. PARTICIPANTS: A total of 2520 community-dwelling 65-year-old to 84-year-old adults in Salisbury, Md, from 1993 to 1995, of whom 26.4% were African Americans. MAIN OUTCOME MEASURE: Association of photographically documented cortical opacity 3/16 or greater in at least 1 eye with ocular UV-B exposure, reported in Maryland sun-years of exposure. RESULTS: The odds of cortical opacity increased with increasing ocular exposure to UV-B (odds ratio [OR], 1.10; 95% confidence interval [CI], 1.02-1.20). The relationship was similar for women (OR, 1.14; 95% CI, 1.00-1.30) and for African Americans (OR, 1.18; 95% CI, 1.04-1.33). Analyses of the ocular dose by each age group after the age of 30 years showed no vulnerable age group, suggesting damage is based on cumulative exposure. CONCLUSIONS: Although this population of older Americans has relatively low ocular exposure to UV-B in sunlight, there is still an association between ocular exposure and increasing odds of cortical opacity. Our study found an association among African Americans, which, to our knowledge, has not been reported previously. All sex and racial groups would benefit from simple methods to avoid ocular sun exposure. SN - 0098-7484 UR - https://www.unboundmedicine.com/medline/citation/9728643/full_citation L2 - https://jamanetwork.com/journals/jama/fullarticle/vol/280/pg/714 DB - PRIME DP - Unbound Medicine ER -