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Feverfew as a preventive treatment for migraine: a systematic review.

Abstract

BACKGROUND

Feverfew is a popular herbal remedy advocated for the prevention of migraine.

AIM

The aim of this systematic review was to look at the evidence for or against the clinical effectiveness of feverfew in migraine prevention.

DATA SOURCES

Literature searches were performed using the following databases: Medline, Embase, Biosis, CISCOM, and the Cochrane Library (all from their inception to April 1998).

STUDY SELECTION

Only randomized, placebo-controlled, double-blind trials were included.

DATA EXTRACTION

All articles were read by two independent reviewers. Data were extracted in a predefined, standardized fashion. The methodological quality of all trials was evaluated using the Jadad score.

MAIN RESULTS

Five trials met the inclusion/exclusion criteria. The majority favor feverfew over placebo. Yet important caveats exist.

CONCLUSION

The clinical effectiveness of feverfew in the prevention of migraine has not been established beyond reasonable doubt.

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  • Publisher Full Text
  • Authors+Show Affiliations

    ,

    Department of Complementary Medicine, School of Postgraduate Medicine and Health Sciences, University of Exeter, UK.

    ,

    Source

    MeSH

    Humans
    Migraine Disorders
    Plant Extracts
    Plants, Medicinal
    Randomized Controlled Trials as Topic
    Sesquiterpenes
    Tanacetum parthenium

    Pub Type(s)

    Journal Article
    Review
    Systematic Review

    Language

    eng

    PubMed ID

    9950629

    Citation

    Vogler, B K., et al. "Feverfew as a Preventive Treatment for Migraine: a Systematic Review." Cephalalgia : an International Journal of Headache, vol. 18, no. 10, 1998, pp. 704-8.
    Vogler BK, Pittler MH, Ernst E. Feverfew as a preventive treatment for migraine: a systematic review. Cephalalgia. 1998;18(10):704-8.
    Vogler, B. K., Pittler, M. H., & Ernst, E. (1998). Feverfew as a preventive treatment for migraine: a systematic review. Cephalalgia : an International Journal of Headache, 18(10), pp. 704-8.
    Vogler BK, Pittler MH, Ernst E. Feverfew as a Preventive Treatment for Migraine: a Systematic Review. Cephalalgia. 1998;18(10):704-8. PubMed PMID: 9950629.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Feverfew as a preventive treatment for migraine: a systematic review. AU - Vogler,B K, AU - Pittler,M H, AU - Ernst,E, PY - 1999/2/9/pubmed PY - 1999/2/9/medline PY - 1999/2/9/entrez SP - 704 EP - 8 JF - Cephalalgia : an international journal of headache JO - Cephalalgia VL - 18 IS - 10 N2 - BACKGROUND: Feverfew is a popular herbal remedy advocated for the prevention of migraine. AIM: The aim of this systematic review was to look at the evidence for or against the clinical effectiveness of feverfew in migraine prevention. DATA SOURCES: Literature searches were performed using the following databases: Medline, Embase, Biosis, CISCOM, and the Cochrane Library (all from their inception to April 1998). STUDY SELECTION: Only randomized, placebo-controlled, double-blind trials were included. DATA EXTRACTION: All articles were read by two independent reviewers. Data were extracted in a predefined, standardized fashion. The methodological quality of all trials was evaluated using the Jadad score. MAIN RESULTS: Five trials met the inclusion/exclusion criteria. The majority favor feverfew over placebo. Yet important caveats exist. CONCLUSION: The clinical effectiveness of feverfew in the prevention of migraine has not been established beyond reasonable doubt. SN - 0333-1024 UR - https://www.unboundmedicine.com/medline/citation/9950629/full_citation L2 - http://journals.sagepub.com/doi/full/10.1111/j.1468-2982.1998.1810704.x?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -