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7,253 results
  • Should continuous dopaminergic stimulation be a standard of care in advanced Parkinson's disease? [Review]
    J Neural Transm (Vienna). 2023 Nov; 130(11):1395-1404.Pirtošek Z, Leta V, … Vérin M
  • The standard of care is a term that refers to the level of care, skill, and treatment that a healthcare provider should offer to a patient based on the current scientific evidence and the level of medical knowledge available in the field. For Parkinson's disease (PD), the standard care is mostly considered to be oral treatment with dopaminergic drugs, particularly levodopa which remains the 'gold…
  • Antinociceptive effects of carbidopa levodopa on normal rats and Parkinson's disease mice. [Journal Article]
    Pak J Pharm Sci. 2023 Sep; 36(5):1489-1495.Wenbo Z, Zhigang M, … Tian W
  • Carbidopa levodopa is widely used to ameliorate motor symptoms of Parkinson's disease (PD) patients. Pain is one of common symptoms of PD. The aim of this experiment is to study antinociceptive effects of carbidopa levodopa on normal rats and PD mice. Rats were intragastrically treated with carbidopa levodopa and the hind paw withdrawal latency (HWL) was investigated. PD mouse model was prepared …
  • Current and novel infusion therapies for patients with Parkinson's disease. [Review]
    J Neural Transm (Vienna). 2023 Nov; 130(11):1349-1358.Antonini A, D'Onofrio V, Guerra A
  • Advanced Parkinson's disease is characterized by periods of poor mobility, dyskinesia and progressive decline in functional independence of the affected person despite the manipulation of levodopa doses and the introduction of supplemental therapies such as catechol-O-methyl transferase inhibitors, monoamine oxidase-B inhibitors and dopamine agonists. The implementation of drug delivery systems a…
  • StatPearls: Alpha Receptor Agonist Toxicity [BOOK]
    StatPearls. StatPearls Publishing: Treasure Island (FL)NormanKennethKSt. Luke's University Health NetworkNappeThomas M.TMSt. Luke's University Health Network; Lewis Katz School of Medicine, Temple UniversityBOOK
  • Alpha-adrenergic agonist toxicity is due to a broad group of pharmaceutical agents known as alpha agonists, which can be further broken down into central alpha-2 agonists and peripheral alpha-1 agonists. Central alpha-2 agonists include clonidine, guanfacine, tizanidine, guanabenz, and methyldopa. Peripheral alpha-1 agonists include imidazoline, oxymetazoline, tetrahydrozoline, and naphazoline. M…
  • Evaluation and Management of Hypertensive Disorders of Pregnancy. [Review]
    Kidney360. 2023 10 01; 4(10):1512-1525.Bajpai D, Popa C, … Shah S
  • Hypertensive disorders of pregnancy complicate up to 10% of pregnancies and remain the major cause of maternal and neonatal morbidity and mortality. Hypertensive disorders of pregnancy can be classified into four groups depending on the onset of hypertension and the presence of target organ involvement: chronic hypertension, preeclampsia, gestational hypertension, and superimposed preeclampsia on…
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