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Used in the treatment of various solid tumors, lymphomas, and leukemias. Also used in some autoimmune disorders such as rheumatoid arthritis (cyclophosphamide, methotrexate). Often used in combinations to minimize individual toxicities and ↑ response. Chemotherapy may be combined with other treatment modalities such as surgery and radiation therapy. Dosages vary greatly, depending on extent of disease, other agents used, and patient's condition. Some agents (doxorubicin, irinotecan) are available in lipid-based formulations that have less toxicity with greater efficacy.
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Quiring, Courtney, et al. "Antineoplastics." Davis's Drug Guide, 16th ed., F.A. Davis Company, 2019. Washington Manual, www.unboundmedicine.com/washingtonmanual/view/Davis-Drug-Guide/50922/all/antineoplastics.
Quiring C, Sanoski CA, Vallerand AH. Antineoplastics. Davis's Drug Guide. 16th ed. F.A. Davis Company; 2019. https://www.unboundmedicine.com/washingtonmanual/view/Davis-Drug-Guide/50922/all/antineoplastics. Accessed September 20, 2019.
Quiring, C., Sanoski, C. A., & Vallerand, A. H. (2019). Antineoplastics. In Davis's Drug Guide. Available from https://www.unboundmedicine.com/washingtonmanual/view/Davis-Drug-Guide/50922/all/antineoplastics
Quiring C, Sanoski CA, Vallerand AH. Antineoplastics [Internet]. In: Davis's Drug Guide. F.A. Davis Company; 2019. [cited 2019 September 20]. Available from: https://www.unboundmedicine.com/washingtonmanual/view/Davis-Drug-Guide/50922/all/antineoplastics.
TY - ELEC
T1 - antineoplastics
ID - 50922
A1 - Quiring,Courtney,
AU - Sanoski,Cynthia A,
AU - Vallerand,April Hazard,
BT - Davis's Drug Guide
UR - https://www.unboundmedicine.com/washingtonmanual/view/Davis-Drug-Guide/50922/all/antineoplastics
PB - F.A. Davis Company
ET - 16
DB - Washington Manual
DP - Unbound Medicine