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Antirheumatics are used to manage symptoms of rheumatoid arthritis (pain, swelling) and in more severe cases to slow down joint destruction and preserve joint function. NSAIDs, aspirin, and other salicylates are used to manage symptoms such as pain and swelling, allowing continued motility and improved quality of life. Corticosteroids are reserved for more advanced swelling and discomfort, primarily because of their ↑ side effects, especially with chronic use. They can be used to control acute flares of disease. Neither NSAIDs nor corticosteroids prevent disease progression or joint destruction. Disease-modifying antirheumatics drugs (DMARDs) slow the progression of rheumatoid arthritis and delay joint destruction. DMARDs are reserved for severe cases because of their toxicity. Several months of therapy may be required before benefit is noted and maintained. Serious and frequent adverse reactions may require discontinuation of therapy, despite initial benefit.
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Quiring, Courtney, et al. "Antirheumatics." Davis's Drug Guide, 16th ed., F.A. Davis Company, 2019. Washington Manual, www.unboundmedicine.com/washingtonmanual/view/Davis-Drug-Guide/50928/all/antirheumatics.
Quiring C, Sanoski CA, Vallerand AH. Antirheumatics. Davis's Drug Guide. 16th ed. F.A. Davis Company; 2019. https://www.unboundmedicine.com/washingtonmanual/view/Davis-Drug-Guide/50928/all/antirheumatics. Accessed August 18, 2019.
Quiring, C., Sanoski, C. A., & Vallerand, A. H. (2019). Antirheumatics. In Davis's Drug Guide. Available from https://www.unboundmedicine.com/washingtonmanual/view/Davis-Drug-Guide/50928/all/antirheumatics
Quiring C, Sanoski CA, Vallerand AH. Antirheumatics [Internet]. In: Davis's Drug Guide. F.A. Davis Company; 2019. [cited 2019 August 18]. Available from: https://www.unboundmedicine.com/washingtonmanual/view/Davis-Drug-Guide/50928/all/antirheumatics.
TY - ELEC
T1 - antirheumatics
ID - 50928
A1 - Quiring,Courtney,
AU - Sanoski,Cynthia A,
AU - Vallerand,April Hazard,
BT - Davis's Drug Guide
UR - https://www.unboundmedicine.com/washingtonmanual/view/Davis-Drug-Guide/50928/all/antirheumatics
PB - F.A. Davis Company
ET - 16
DB - Washington Manual
DP - Unbound Medicine