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Biological studies on 1,2-benzisothiazole derivatives. I. Evaluation of antibacterial, antifungal and DNA-damaging activity.
Farmaco. 1989 May; 44(5):511-7.F

Abstract

The in vitro evaluation of antibacterial, antifungal and DNA-damaging properties of some 1,2-benzisothiazole compounds is described. Among all the tested compounds, XXX exhibited the highest antimicrobial activity. A selective antibacterial or antifungal activity was observed for compounds XXI, XXXI and XXXVI. Some of the compounds tested, turned out to have genotoxic properties.

Authors+Show Affiliations

Vicini P
Istituto di Chimica Farmaceutica e Tossicologica, Università di Parma, Italy.
Mazza P
No affiliation info available

MeSH

Anti-Bacterial AgentsAntifungal AgentsBacillus subtilisBacteriaChemical PhenomenaChemistryDNA DamageMutagensRecombination, GeneticThiazoles

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

2506877

Citation

Vicini, P, and P Mazza. "Biological Studies On 1,2-benzisothiazole Derivatives. I. Evaluation of Antibacterial, Antifungal and DNA-damaging Activity." Farmaco (Societa Chimica Italiana : 1989), vol. 44, no. 5, 1989, pp. 511-7.
Vicini P, Mazza P. Biological studies on 1,2-benzisothiazole derivatives. I. Evaluation of antibacterial, antifungal and DNA-damaging activity. Farmaco. 1989;44(5):511-7.
Vicini, P., & Mazza, P. (1989). Biological studies on 1,2-benzisothiazole derivatives. I. Evaluation of antibacterial, antifungal and DNA-damaging activity. Farmaco (Societa Chimica Italiana : 1989), 44(5), 511-7.
Vicini P, Mazza P. Biological Studies On 1,2-benzisothiazole Derivatives. I. Evaluation of Antibacterial, Antifungal and DNA-damaging Activity. Farmaco. 1989;44(5):511-7. PubMed PMID: 2506877.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Biological studies on 1,2-benzisothiazole derivatives. I. Evaluation of antibacterial, antifungal and DNA-damaging activity. AU - Vicini,P, AU - Mazza,P, PY - 1989/5/1/pubmed PY - 1989/5/1/medline PY - 1989/5/1/entrez SP - 511 EP - 7 JF - Farmaco (Societa chimica italiana : 1989) JO - Farmaco VL - 44 IS - 5 N2 - The in vitro evaluation of antibacterial, antifungal and DNA-damaging properties of some 1,2-benzisothiazole compounds is described. Among all the tested compounds, XXX exhibited the highest antimicrobial activity. A selective antibacterial or antifungal activity was observed for compounds XXI, XXXI and XXXVI. Some of the compounds tested, turned out to have genotoxic properties. SN - 0014-827X UR - https://www.unboundmedicine.com/medline/citation/2506877/ DB - PRIME DP - Unbound Medicine ER -

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