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Effect of Platelet Rich Plasma versus Saline Solution as a Preservation Solution for Hair Transplantation.
Plast Reconstr Surg Glob Open. 2020 Jun; 8(6):e2875.PR

Abstract

BACKGROUND

Hair transplantation is the only method available to regrow new hairs; hence, enhancing the results of this procedure using state-of-the-art methods has become mandatory in clinical practice. Recent studies have suggested that significant improvements in hair density and stimulation of hair growth occur when follicular units are pretreated with platelet plasma growth factors before implantation. This study aimed to investigate and compare the outcomes of this procedure using platelet-rich plasma (PRP)-preserved hair grafts and saline-preserved hair grafts.

METHODS

This is a randomized controlled study. The study included 27 men and 3 women aged 22-51 years. Clinical examination (general and local) and preoperative marking were performed in these patients. The surgical technique involved graft extraction, PRP preparation, and hair implantation. Postsurgical patient satisfaction and clinical improvement were evaluated.

RESULTS

There were significant differences between the groups in hair uptake and hair thickness after 1 year follow-up, with P value <0.05. Using PRP therapy with follicular unit extraction increases the success of follicular unit extraction hair transplantation. All participants in the PRP group had >75% hair regrowth after 6 months. They had more rapid improvements in hair density and skin recovery than those in the non-PRP group.

CONCLUSION

Preserving hair grafts in PRP before implantation increases the hair density, the graft uptake, and the hair thickness compared with pretreatment preservation of hair grafts in saline.

Links

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Authors+Show Affiliations

Abdelkader R
Department of Plastic Surgery, Alkasr Allni Hospital, Cairo University, Cairo, Egypt.
Abdalbary S
Orthopaedic Physical Therapy Department, Alkasr Alainy Hospital, Cairo University, Cairo, Egpyt.
Naguib I
Department of Plastic Surgery, Alkasr Allni Hospital, Cairo University, Cairo, Egypt.
Makarem K
Department of Plastic Surgery, Alkasr Allni Hospital, Cairo University, Cairo, Egypt.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32766042

Citation

Abdelkader, Rasha, et al. "Effect of Platelet Rich Plasma Versus Saline Solution as a Preservation Solution for Hair Transplantation." Plastic and Reconstructive Surgery. Global Open, vol. 8, no. 6, 2020, pp. e2875.
Abdelkader R, Abdalbary S, Naguib I, et al. Effect of Platelet Rich Plasma versus Saline Solution as a Preservation Solution for Hair Transplantation. Plast Reconstr Surg Glob Open. 2020;8(6):e2875.
Abdelkader, R., Abdalbary, S., Naguib, I., & Makarem, K. (2020). Effect of Platelet Rich Plasma versus Saline Solution as a Preservation Solution for Hair Transplantation. Plastic and Reconstructive Surgery. Global Open, 8(6), e2875. https://doi.org/10.1097/GOX.0000000000002875
Abdelkader R, et al. Effect of Platelet Rich Plasma Versus Saline Solution as a Preservation Solution for Hair Transplantation. Plast Reconstr Surg Glob Open. 2020;8(6):e2875. PubMed PMID: 32766042.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effect of Platelet Rich Plasma versus Saline Solution as a Preservation Solution for Hair Transplantation. AU - Abdelkader,Rasha, AU - Abdalbary,Sahar, AU - Naguib,Ibrahim, AU - Makarem,Kyrillos, Y1 - 2020/06/25/ PY - 2019/11/20/received PY - 2020/4/9/accepted PY - 2020/8/9/entrez PY - 2020/8/9/pubmed PY - 2020/8/9/medline SP - e2875 EP - e2875 JF - Plastic and reconstructive surgery. Global open JO - Plast Reconstr Surg Glob Open VL - 8 IS - 6 N2 - BACKGROUND: Hair transplantation is the only method available to regrow new hairs; hence, enhancing the results of this procedure using state-of-the-art methods has become mandatory in clinical practice. Recent studies have suggested that significant improvements in hair density and stimulation of hair growth occur when follicular units are pretreated with platelet plasma growth factors before implantation. This study aimed to investigate and compare the outcomes of this procedure using platelet-rich plasma (PRP)-preserved hair grafts and saline-preserved hair grafts. METHODS: This is a randomized controlled study. The study included 27 men and 3 women aged 22-51 years. Clinical examination (general and local) and preoperative marking were performed in these patients. The surgical technique involved graft extraction, PRP preparation, and hair implantation. Postsurgical patient satisfaction and clinical improvement were evaluated. RESULTS: There were significant differences between the groups in hair uptake and hair thickness after 1 year follow-up, with P value <0.05. Using PRP therapy with follicular unit extraction increases the success of follicular unit extraction hair transplantation. All participants in the PRP group had >75% hair regrowth after 6 months. They had more rapid improvements in hair density and skin recovery than those in the non-PRP group. CONCLUSION: Preserving hair grafts in PRP before implantation increases the hair density, the graft uptake, and the hair thickness compared with pretreatment preservation of hair grafts in saline. SN - 2169-7574 UR - https://www.unboundmedicine.com/medline/citation/32766042/ DB - PRIME DP - Unbound Medicine ER -
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