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Trichoscopy as an evaluation method for alopecia areata treatment: A comparative study.
J Cosmet Dermatol. 2021 Jun; 20(6):1827-1836.JC

Abstract

BACKGROUND

Trichoscopy is a useful tool for diagnosis and follow-up of alopecia areata (AA) patients. Both platelet-rich plasma (PRP) and intralesional corticosteroids (ILCs) are important treatment modalities of patchy AA.

AIM

Trichoscopic diagnosis of AA and monitoring the treatment response to PRP versus ILCs in patchy AA treatment.

PATIENTS/METHODS

This comparative study included 31 patients with patchy AA, divided into two groups: (group A) received ILCs while (group B) received PRP once monthly for 3 months. Evaluation was done by Severity of Alopecia Tool (SALT) score, Alopecia Areata Symptom Impact Scale (AASIS), photography, and dermoscopy.

RESULTS

There was a significant improvement in trichoscopic findings in both groups with regard to the number of follicular units per opening, black dots, broken hairs, and dystrophic changes. Final SALT score showed significant lower levels in both groups compared to baseline levels (P = .025 & P = .008). Final AASIS showed significant decrease in group B (P = .006) not in group A (P = .062).

CONCLUSION

Trichoscopy can help in the diagnosis, evaluation of the efficacy and safety of both modalities and might give a clue for treatment response. Both ILCs and PRP were effective in patchy AA treatment.

Authors+Show Affiliations

Dermatology Department, Faculty of Medicine, Cairo University, New Cairo, Egypt.Dermatology Department, Faculty of Medicine, Cairo University, New Cairo, Egypt.Department of Dermatology and Venereology, National Research Centre, Giza, Egypt.Dermatology Department, Faculty of Medicine, Cairo University, New Cairo, Egypt.Dermatology Department, Faculty of Medicine, Cairo University, New Cairo, Egypt.Dermatology Department, Faculty of Medicine, Cairo University, New Cairo, Egypt.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32991045

Citation

Fawzy, Marwa M., et al. "Trichoscopy as an Evaluation Method for Alopecia Areata Treatment: a Comparative Study." Journal of Cosmetic Dermatology, vol. 20, no. 6, 2021, pp. 1827-1836.
Fawzy MM, Abdel Hay R, Mohammed FN, et al. Trichoscopy as an evaluation method for alopecia areata treatment: A comparative study. J Cosmet Dermatol. 2021;20(6):1827-1836.
Fawzy, M. M., Abdel Hay, R., Mohammed, F. N., Sayed, K. S., Ghanem, M. E. D., & Ezzat, M. (2021). Trichoscopy as an evaluation method for alopecia areata treatment: A comparative study. Journal of Cosmetic Dermatology, 20(6), 1827-1836. https://doi.org/10.1111/jocd.13739
Fawzy MM, et al. Trichoscopy as an Evaluation Method for Alopecia Areata Treatment: a Comparative Study. J Cosmet Dermatol. 2021;20(6):1827-1836. PubMed PMID: 32991045.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Trichoscopy as an evaluation method for alopecia areata treatment: A comparative study. AU - Fawzy,Marwa M, AU - Abdel Hay,Rania, AU - Mohammed,Faisal Nouredin, AU - Sayed,Khadiga S, AU - Ghanem,Mona El Desoky, AU - Ezzat,Marwa, Y1 - 2020/10/13/ PY - 2020/08/26/revised PY - 2020/06/12/received PY - 2020/09/17/accepted PY - 2020/9/30/pubmed PY - 2021/5/25/medline PY - 2020/9/29/entrez KW - Alopecia areata KW - SALT score KW - dermoscopy KW - intralesional corticosteroids KW - platelet-rich plasma SP - 1827 EP - 1836 JF - Journal of cosmetic dermatology JO - J Cosmet Dermatol VL - 20 IS - 6 N2 - BACKGROUND: Trichoscopy is a useful tool for diagnosis and follow-up of alopecia areata (AA) patients. Both platelet-rich plasma (PRP) and intralesional corticosteroids (ILCs) are important treatment modalities of patchy AA. AIM: Trichoscopic diagnosis of AA and monitoring the treatment response to PRP versus ILCs in patchy AA treatment. PATIENTS/METHODS: This comparative study included 31 patients with patchy AA, divided into two groups: (group A) received ILCs while (group B) received PRP once monthly for 3 months. Evaluation was done by Severity of Alopecia Tool (SALT) score, Alopecia Areata Symptom Impact Scale (AASIS), photography, and dermoscopy. RESULTS: There was a significant improvement in trichoscopic findings in both groups with regard to the number of follicular units per opening, black dots, broken hairs, and dystrophic changes. Final SALT score showed significant lower levels in both groups compared to baseline levels (P = .025 & P = .008). Final AASIS showed significant decrease in group B (P = .006) not in group A (P = .062). CONCLUSION: Trichoscopy can help in the diagnosis, evaluation of the efficacy and safety of both modalities and might give a clue for treatment response. Both ILCs and PRP were effective in patchy AA treatment. SN - 1473-2165 UR - https://www.unboundmedicine.com/medline/citation/32991045/ DB - PRIME DP - Unbound Medicine ER -