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[Cognitive impairment in patients with chronic heart failure and its impact on adherence to treatment].
Ter Arkh. 2025 Jul 31; 97(7):562-570.TA

Abstract

AIM

To evaluate cognitive impairment in patients with chronic heart failure (CHF) and its impact on treatment adherence.

MATERIALS AND METHODS

The study included 120 hospitalized patients with CHF regardless of left ventricular ejection fraction aged from 20 to 79 years with different etiology of CHF. All patients underwent complex neuropsychological testing to determine the presence and severity of CH, psychoemotional status, as well as adherence to treatment and quality of life. After 6 months, the group of patients who came for a follow-up visit was re-evaluated for these indicators. The first group of patients was compared with the second group of patients who did not come for a follow-up visit after 6 months, although the conditions of the study were explained to all single patients.

RESULTS

Out of 120 patients, 28 (23.3%) patients came for a follow-up visit, 3 (2.5%) patients died, the rest of the study participants [89 (74.2%) patients] - refused a face-to-face visit to the physician. On MoCA after 6 months, patients showed a higher mean score of 23.89±2.67 (p=0.003). Percentage-wise, 53.6% of patients showed improvement in cognitive functioning scores. Group 1 patients (n=28) demonstrated a medium relationship between treatment adherence on the Morisky-Green questionnaire and RBM-7 (r=-0.532) in contrast to group 2 patients (n=89) who demonstrated a weak relationship (r=-0.283).

CONCLUSION

The complex relationship between CHF and cognitive impairment emphasizes the need for a comprehensive approach to patient care. Patients who demonstrate high compliance and good subjective assessment of their cognitive functioning, although some cognitive functions are reduced, are the most motivated to comply with the doctor's recommendations and follow-up.

Authors+Show Affiliations

Chazov National Medical Research Center of Cardiology.Chazov National Medical Research Center of Cardiology.Chazov National Medical Research Center of Cardiology.Chazov National Medical Research Center of Cardiology. Russian Medical Academy of Continuous Professional Education.Mental Health Research Center.Mental Health Research Center. Lomonosov Moscow State University.Mental Health Research Center. Lomonosov Moscow State University.Lomonosov Moscow State University.The Doctor is Nearby LLC.Chazov National Medical Research Center of Cardiology.

Pub Type(s)

English Abstract
Journal Article

Language

rus

PubMed ID

40778917

Citation

Aksenova, Y O., et al. "[Cognitive Impairment in Patients With Chronic Heart Failure and Its Impact On Adherence to Treatment]." Terapevticheskii Arkhiv, vol. 97, no. 7, 2025, pp. 562-570.
Aksenova YO, Petrukhina AA, Osmolovskaya YF, et al. [Cognitive impairment in patients with chronic heart failure and its impact on adherence to treatment]. Ter Arkh. 2025;97(7):562-570.
Aksenova, Y. O., Petrukhina, A. A., Osmolovskaya, Y. F., Zhirov, I. V., Beniashvili, A. G., Morozova, M. A., Rupchev, G. E., Galich, A. A., Tolstukhina, O. N., & Tereshchenko, S. N. (2025). [Cognitive impairment in patients with chronic heart failure and its impact on adherence to treatment]. Terapevticheskii Arkhiv, 97(7), 562-570. https://doi.org/10.26442/00403660.2025.07.203351
Aksenova YO, et al. [Cognitive Impairment in Patients With Chronic Heart Failure and Its Impact On Adherence to Treatment]. Ter Arkh. 2025 Jul 31;97(7):562-570. PubMed PMID: 40778917.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Cognitive impairment in patients with chronic heart failure and its impact on adherence to treatment]. AU - Aksenova,Y O, AU - Petrukhina,A A, AU - Osmolovskaya,Y F, AU - Zhirov,I V, AU - Beniashvili,A G, AU - Morozova,M A, AU - Rupchev,G E, AU - Galich,A A, AU - Tolstukhina,O N, AU - Tereshchenko,S N, Y1 - 2025/07/31/ PY - 2025/01/28/received PY - 2025/07/31/accepted PY - 2025/01/30/revised PY - 2025/8/8/medline PY - 2025/8/8/pubmed PY - 2025/8/8/entrez KW - adherence to treatment KW - chronic heart failure KW - cognitive impairment KW - compliance SP - 562 EP - 570 JF - Terapevticheskii arkhiv JO - Ter Arkh VL - 97 IS - 7 N2 - AIM: To evaluate cognitive impairment in patients with chronic heart failure (CHF) and its impact on treatment adherence. MATERIALS AND METHODS: The study included 120 hospitalized patients with CHF regardless of left ventricular ejection fraction aged from 20 to 79 years with different etiology of CHF. All patients underwent complex neuropsychological testing to determine the presence and severity of CH, psychoemotional status, as well as adherence to treatment and quality of life. After 6 months, the group of patients who came for a follow-up visit was re-evaluated for these indicators. The first group of patients was compared with the second group of patients who did not come for a follow-up visit after 6 months, although the conditions of the study were explained to all single patients. RESULTS: Out of 120 patients, 28 (23.3%) patients came for a follow-up visit, 3 (2.5%) patients died, the rest of the study participants [89 (74.2%) patients] - refused a face-to-face visit to the physician. On MoCA after 6 months, patients showed a higher mean score of 23.89±2.67 (p=0.003). Percentage-wise, 53.6% of patients showed improvement in cognitive functioning scores. Group 1 patients (n=28) demonstrated a medium relationship between treatment adherence on the Morisky-Green questionnaire and RBM-7 (r=-0.532) in contrast to group 2 patients (n=89) who demonstrated a weak relationship (r=-0.283). CONCLUSION: The complex relationship between CHF and cognitive impairment emphasizes the need for a comprehensive approach to patient care. Patients who demonstrate high compliance and good subjective assessment of their cognitive functioning, although some cognitive functions are reduced, are the most motivated to comply with the doctor's recommendations and follow-up. SN - 0040-3660 UR - https://www.unboundmedicine.com/medline/citation/40778917/ DB - PRIME DP - Unbound Medicine ER -