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Evaluation of the accuracy of on-site multi-analyte drug testing devices in the determination of the prevalence of illicit drugs in drivers.
J Forensic Sci. 1998 Mar; 43(2):395-9.JF

Abstract

A principal goal of this research was to conduct a field evaluation of "on-site" multi-analyte drug testing devices to determine the most accurate, efficient, and cost-effective device available for the purpose of rapidly detecting drivers under the influence of drugs. Four on-site kits were selected and evaluated for accuracy and efficiency for the detection of tetrahydrocannabinol (THC), the cocaine metabolites (COC), and opiates (OPI). From 16 December 1995 to 17 March 1996, 303 voluntary urine specimens were collected by law enforcement officers from persons arrested for driving-under-the-influence (DUI). These specimens were tested using the four selected kits and aliquots of the specimens were sent to a DHHS certified lab for "gold standard" comparison testing by immunoassay and Gas Chromatography/Mass Spectrometry. On-site kit sensitivity ranged from 82.9% to 100% for THC, 82.5% to 100% for COC, and all were at 100% for OPI. Specificity, and positive and negative predictive values were also determined. Accuracy ranged from 94.0% to 98.3% for THC, 97.4% to 98.0% for COC, and 99.7% to 100% for OPI. All four kits were in very close agreement on prevalence: 15.5% to 15.8% for THC, all were at 13.2% for COC, and all were at 0.7% for OPI. For law enforcement purposes, sensitivity may be the most important indicator in these kits.

Authors+Show Affiliations

Buchan BJ
Dept. of Epidemiology & Biostatistics, Univ. of South Florida College of Public Health, Tampa, USA.
Walsh JM
No affiliation info available
Leaverton PE
No affiliation info available

MeSH

Automobile DrivingCocaineCost-Benefit AnalysisDronabinolEvaluation Studies as TopicGas Chromatography-Mass SpectrometryHumansNarcoticsPredictive Value of TestsPrevalenceRadioimmunoassayReagent Kits, DiagnosticReproducibility of ResultsSensitivity and SpecificitySubstance Abuse DetectionSubstance-Related Disorders

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

9544550

Citation

Buchan, B J., et al. "Evaluation of the Accuracy of On-site Multi-analyte Drug Testing Devices in the Determination of the Prevalence of Illicit Drugs in Drivers." Journal of Forensic Sciences, vol. 43, no. 2, 1998, pp. 395-9.
Buchan BJ, Walsh JM, Leaverton PE. Evaluation of the accuracy of on-site multi-analyte drug testing devices in the determination of the prevalence of illicit drugs in drivers. J Forensic Sci. 1998;43(2):395-9.
Buchan, B. J., Walsh, J. M., & Leaverton, P. E. (1998). Evaluation of the accuracy of on-site multi-analyte drug testing devices in the determination of the prevalence of illicit drugs in drivers. Journal of Forensic Sciences, 43(2), 395-9.
Buchan BJ, Walsh JM, Leaverton PE. Evaluation of the Accuracy of On-site Multi-analyte Drug Testing Devices in the Determination of the Prevalence of Illicit Drugs in Drivers. J Forensic Sci. 1998;43(2):395-9. PubMed PMID: 9544550.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Evaluation of the accuracy of on-site multi-analyte drug testing devices in the determination of the prevalence of illicit drugs in drivers. AU - Buchan,B J, AU - Walsh,J M, AU - Leaverton,P E, PY - 1998/4/17/pubmed PY - 1998/4/17/medline PY - 1998/4/17/entrez SP - 395 EP - 9 JF - Journal of forensic sciences JO - J Forensic Sci VL - 43 IS - 2 N2 - A principal goal of this research was to conduct a field evaluation of "on-site" multi-analyte drug testing devices to determine the most accurate, efficient, and cost-effective device available for the purpose of rapidly detecting drivers under the influence of drugs. Four on-site kits were selected and evaluated for accuracy and efficiency for the detection of tetrahydrocannabinol (THC), the cocaine metabolites (COC), and opiates (OPI). From 16 December 1995 to 17 March 1996, 303 voluntary urine specimens were collected by law enforcement officers from persons arrested for driving-under-the-influence (DUI). These specimens were tested using the four selected kits and aliquots of the specimens were sent to a DHHS certified lab for "gold standard" comparison testing by immunoassay and Gas Chromatography/Mass Spectrometry. On-site kit sensitivity ranged from 82.9% to 100% for THC, 82.5% to 100% for COC, and all were at 100% for OPI. Specificity, and positive and negative predictive values were also determined. Accuracy ranged from 94.0% to 98.3% for THC, 97.4% to 98.0% for COC, and 99.7% to 100% for OPI. All four kits were in very close agreement on prevalence: 15.5% to 15.8% for THC, all were at 13.2% for COC, and all were at 0.7% for OPI. For law enforcement purposes, sensitivity may be the most important indicator in these kits. SN - 0022-1198 UR - https://www.unboundmedicine.com/medline/citation/9544550/ L2 - https://www.who.int/reproductivehealth/publications/cancers/a92126/en/ DB - PRIME DP - Unbound Medicine ER -

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